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In the animal experiments, animals were randomly grouped and coded by an independent individual, and both the experimenters and data analysts were blinded to the group allocations
Sources SURMOUNT-1 trial (Jastreboff et al., New England Journal of Medicine, 2022) primary clinical trial reporting GI side-effect rates by dose for tirzepatide
Whether a washout period is needed : Your prescriber will determine if you need to wait before starting the new medication, especially if you've been experiencing side effects
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