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In conclusion, the GLP-1/GLP-1R signalling plays a significant role in the balance of innate immunity, particularly in the polarisation of macrophages
During meals, GLP-1 is secreted in two stages: a first peak occurs approximately 15 min after the beginning of the meal, when food in the stomach and in the initial portions of the intestine stimulates the release of hormones, such as glucose-dependent insulinotropic polypeptide (GIP), which acts by vagal pathways to stimulate L cells [12]
Ruigrok SR, Yim K, Emmerzaal TL, Geenen B, Stberl N, den Blaauwen JL, et al
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