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B., Idorn, T., Mahaffey, K
Culturing PDAC cell lines in cystine deficient conditions induces cell death in more than 80% of cells, which is rescued by the addition of antioxidant Trolox
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The relative activities among ACPC-containing analogues of the two natural GLP-1R agonists were consistent with predictions of our hypothesis: the Gly10( R,R )-ACPC analogue of GLP-1 was ~9-fold more potent than the ( S,S )-ACPC diastereomer, and the Gly4( R,R )-ACPC analogue of exendin-4 was ~5-fold more potent than the ( S,S )-ACPC diastereomer in eliciting cAMP production (Fig
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