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One major limitation of our current understanding is the lack of large intervention studies, as the available insights are mainly deduced from trials enrolling fewer than 100 patients, necessitating the attempt to conduct meta-analyses on results from not always fully comparable trials

Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all- trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers

The kinetics of serum miR-122 appears to be closely following the response of the translational biomarker ALT, but more work is needed to determine this

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