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Furthermore, MSM can increase the monolayer transepithelial electrical resistance and upregulate the expression of tight junction proteins (occludin, claudin-1, and zonula occludens-1), while reducing the permeability of porcine intestinal epithelial cells [43]
Magnesium citrate or magnesium glycinate at 200-300 mg daily is commonly used by GLP-1 users for constipation because it draws water into the colon and supports peristalsis
Diabetes 57:13401348 Shu L, Matveyenko AV, Kerr-Conte J, Cho JH, McIntosh CH, Maedler K (2009) Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
Youll take this once a week for a month before increasing your dose
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