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Some advantages were concluded that ketone bodies produced in these diets could serve as an alternative energy source for the brain (62), and during 3-day cycles of a fasting mimicking diet, it was found that the clinical symptoms of experimental autoimmune encephalomyelitis mice
GLP-1 therapies influence pathways tied to addiction and reward, according to the Endocrine Society A randomized clinical trial published in JAMA Psychiatry found semaglutide reduced alcohol cravings and consumption Users commonly report: Reduced desire to drink Feeling full faster when drinking Less reward from alcohol The data: early, but directionally consistent While long-term industry sales data is still developing, the early signals from clinical studies, observational research, and population polling all point in the same direction: GLP-1 use is associated with lower alcohol consumption for at least some users
At present, the available evidence suggests that both GLP-1 agonist and SGLT2 inhibitors produce unfavourable outcomes, and should be avoided in pregnancy and during lactation
