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Drucker, a clinician scientist at Sinai Healths Lunenfeld-Tanenbaum Research Institute and a former member of Habeners MGH research group uncovered more of GLP-1s physiological actions and helped translate GLP-1s therapeutic benefits to drugs

Though there has been some rudimentary research work indicating that the GLP-1 receptor agonists can indirectly provide mood-enhancing effects by regulating the dopamine reward system, lessening inflammatory responses, or improving metabolic status, adverse events that have been observed in real life studies and case reports can suggest that their action at the central nervous system is more complicated [11, 16, 17]

Diabetes 61:12501262 Nachnani JS, Bulchandani DG, Nookala A et al (2010) Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas