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A user who sees 60% improvement in a first cycle might gain another 20 to 30% in a second cycle after a rest period
While no large trial has tested creatine specifically in GLP-1 users, the mechanism is relevant: creatine improves training performance, and better training performance means more muscle stimulus during a deficit
You will likely see a pattern emerge, which makes it easier to plan your meals and activities in the following weeks
Since the progression to invasive PDAC is believed to take more than a decade, the follow-up periods in many cohort studies and randomized controlled trials (where it is typically 12 years) are insufficient to understand the long-term effects
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