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Cells producing and secreting enteroglucagon were originally identified by immunohistochemistry with glucagon antibodies and it was noted that the cells in the gut mucosa differed from islet -cells that produce glucagon (42)
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In 1987 he and Bernhard Kreymann launched a study with other colleagues to investigate the physiological effect of another synthesised fragment of human GLP-1 directly in humans
Although -MSH level was roughly 500-fold higher in the pituitary gland, which is the main source of -MSH production, -MSH concentration in other reference tissues such as the spleen and skeletal muscle was considerably lower compared to the heart (Fig
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