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Effect of porcine gastric inhibitory polypeptide on beta-cell function in type I and type II diabetes mellitus

With GSH depleted, TCR signal transduction is blunted, reducing T-cell proliferation and protective cytokine output

In clinical trials, including a Phase 2 study published in the New England Journal of Medicine (2023), it has been administered as a subcutaneous injection injected beneath the skin typically once weekly