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Why Patients Fear a Herxheimer Reaction Patients often describe fear when symptoms worsen after starting treatment
In non-diabetic models, it induces endothelial injury via NOX2-dependent oxidative stress, increasing NF-B levels and vascular inflammation/early atherosclerosis (Huang, 2023)
10.1182/blood-2011-12-398818 142 Rosenbaum-KrummeS
But more recently, GLP-1s have made headlines for their role in slowing digestion and reducing appetite, helping to prevent blood sugar spikes and increasing feelings of fullness
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