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Zolbetuximab, the first monoclonal antibody targeting CLDN18.2, significantly improved PFS and OS compared with chemotherapy alone in two phase III trials
Nevertheless, bioinformatic analysis has suggested that viral mimicry of host SLiMs is a common strategy for viral takeover 16 , and many questions remain to be answered by systematic and unbiased pan-viral studies
These UV-independent melanogenesis studies have established MT-1 as the reference tool for dissecting MC1R-specific pigmentation biology from UV-dependent mechanisms
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