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Like tirzepatide, semaglutide is typically taken on a weekly schedule, with doses increased gradually over time
Acknowledgements The authors apologize for incomplete citations owing to rapid advancement of the field
47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF
Do not swallow the tablet directly
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