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MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)
Additionally, fatigue emerged as a frequently discussed symptom, despite being less prominent in clinical trial data
Coverage also depends on whether your employer group included weight-loss drugs in the benefit design
BioMed research international , 2013 , 783809
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