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Semaglutide is a GLP-1-only agonist, while tirzepatide activates both GLP-1 and GIP receptors simultaneously, producing stronger appetite suppression and metabolic effects in many patients

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doi: 10.1111/ijcp.13731 Summary Keywords body weight, glycated hemoglobin (HbA 1c ), efficacy, glucagon-like peptide-1 receptor agonist (GLP-1RA), oral, semaglutide, subcutaneous, type 2 diabetes Citation Meier JJ (2021) Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation