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Richies research is to examine the role of glutathionethe major endogenous antioxidant in nearly all cells and tissuesin protecting against oxidative damage during aging and its relationship with cancer development at numerous sites
Vitamins C and E: Enhances their lifespan and effectiveness
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Considering the positive impact of Nrf2 in ameliorating oxidative stress, a number of bioactive components that exert protective effect against APAP-associated hepatotoxicity have been identified and reported, including caffeic acid that activates the Keap1-Nrf2 antioxidant defense system (Pang et al., 2016), carnosic acid that promotes nuclear translocation of Nrf2 ( via AMP-activated kinase/Akt/glycogen synthase kinase 3 pathway (Wang et al., 2016)
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