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Change history 16 May 2025 Editors Note: Readers are alerted that concerns have been raised regarding the statistical analysis presented in this article

VLDLy is a small, estrogen-modified VLDL subclass (40 nm) characterized by resistance to peripheral lipoprotein lipase hydrolysis, allowing it to bypass extrahepatic tissues and deliver DHA-rich TG and phospholipids directly to the ovary ( 3.3.4 Selective deposition of DHA in yolk Among dietary fatty acids, DHA exhibits a pronounced selective advantage for yolk deposition

Furthermore, the RCTs needed to be performed on OMMs approved by the EMA and available in at least one EASO member country as of 21 November 2025