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p53 could suppress MTHFD2 transcription, and MTHFD2 upregulation by p53 inactivation results in enhanced one-carbon metabolism, purine biosynthesis and tumor proliferation (Pikman et al., 2016
Avoid high-fat, greasy, or heavily spiced foods
Fatty liver diseases The increasing incidence of metabolic dysfunction-associated fatty liver disease (MAFLD
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