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Weight loss, particularly rapid weight loss often seen with these drugs, inevitably involves the loss of both fat mass and lean body mass (muscle)
Nature 426:570574 Bond J, Roberts E, Springell K, Lizarraga SB, Scott S, Higgins J, Hampshire DJ, Morrison EE, Leal GF, Silva EO, Costa SM, Baralle D, Raponi M, Karbani G, Rashid Y, Jafri H, Bennett C, Corry P, Walsh CA, Woods CG (2005) A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
Creatine is the most effective supplement for increasing muscle mass and strength L-Carnitine helps the body convert fat to energy by transporting fats into mitochondria for beta-oxidation and energy production