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Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

Desiree Granados Quick Summary: Semaglutide and phentermine are weight-management medications with different mechanisms: semaglutide activates GLP-1 receptors to reduce appetite and improve glycemic control with sustained outcomes, while phentermine primarily acts as a stimulant to suppress appetite short-term

The accelerated approval requires confirmatory evidence from the ESSENCE trial and other ongoing studies to validate long-term clinical benefit.