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A higher level of oxidative stress was detected in patients with NASH compared to NAFLD and a reduction in the levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and GGT, as markers of oxidative stress, was highlighted in NASH patients treated with GSH, with a consequent reduction of alanine transaminase (ALT)
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Clinical observation and animal studies suggest the new class of weight loss medications like semaglutide and tirzepatide best known by brand name medications like Ozempic and Zepbound, respectively might help address substance use disorder as well, yet focused research in this area is limited
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