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Common side effects include gastrointestinal symptoms with GLP-1 receptor agonists and genitourinary infections with SGLT2 inhibitors

Store unreconstituted vials refrigerated or frozen and protected from light

Experimental evidence showed that activating mitophagy through genetic or pharmacological approaches, especially in the early stages of oxidative stress, can significantly reduce the risk of ferroptosis by clearing and degrading damaged mitochondria, possibly by preventing subsequent metabolic abnormalities from generating excess ROS [115]