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The allocation to treatment sequence was randomized 1:1 on the basis of a prefabricated randomization list of the Clinical Trial Unit Basel integrated into the electronic data capture system

It exists to serve real needs: a patient who cannot tolerate a dye in a commercial tablet, a child who needs a liquid version of a drug sold only as a capsule, a formulation a manufacturer does not make

(7) hyperinsulinism as an energetic response to chronic cellular injury

While complete Phase 3 data is pending, the trial design incorporates the escalation framework validated in Phase 2 starting at lower doses and escalating over defined intervals to target maintenance doses