TRIUMPH-4: knee osteoarthritis (completed) TRIUMPH-4 is the first and, as of April 2026, the only Phase 3 trial to report results
Sessions typically last 60-90 minutes and are known to deliver noticeable benefits with minimal discomfort
Mildly affected patients have mutations affecting the stability of the enzyme, causing a compensated hemolytic anemia
Gravelat FN, Beauvais A, Liu H, Lee MJ, Snarr BD, Chen D, Xu W, Kravtsov I, Hoareau CM, Vanier G, Urb M, Campoli P, Al Abdallah Q, Lehoux M, Chabot JC, Ouimet MC, Baptista SD, Fritz JH, Nierman WC, Latg JP, Mitchell AP, Filler SG, Fontaine T, Sheppard DC (2013) Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal -glucan from the immune system