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30 days (reconstituted) Mechanism Classification Primary Mechanism: NNMT (Nicotinamide N-methyltransferase) Inhibitor Target Enzyme: Nicotinamide N-methyltransferase Cellular Effect: Increases intracellular NAD+ and SAM levels Metabolic Pathway: NAD+ salvage pathway modulation Selectivity: Highly selective for NNMT (no cross-reactivity with related enzymes) Pharmacological Properties Route of Administration: Subcutaneous injection Bioavailability: High (subcutaneous)
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Materials and methods Strains, Plasmids and growth conditions Bacterial strains and plasmids used in this study are listed in Supplementary tables S1 and S2
The peptide does not affect liver metabolism in ways that would interact with alcohol processing
