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Ann Hepatol 2015;14:299-303

Although the beneficial role of liraglutide in osteoarthritis has long been acknowledged, it was not until recently that a study hypothesized this GLP-1RA mediated macrophage transition to an M2 anti-inflammatory phenotype, inhibiting pro-inflammatory cytokine release in a dose-dependent manner (Meurot et al., 2022)

Research continues, but immediate approval in this indication now appears unlikely

With innovation spanning long-acting injectables, oral GLP-1s, and dual agonist combinations, pharmaceutical leaders are accelerating next-generation treatment accessibility and patient convenience