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Key hormones like GLP-1, leptin, ghrelin, and CCK act as crucial messengers, directly regulating the sensitivity and expression of peripheral taste receptors, while central neuromodulators, such as dopamine and serotonin, integrate these signals with reward and homeostatic circuits (172, 182)
The expression level of pyruvate dehydrogenase (encoding by aceE ), which catalyzes the reaction from pyruvate to the formation of acetyl-CoA, was only 0.13-fold in MG12345
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