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The activation of this complex induces the self-cleavage of pro-caspase-1 into active caspase-1, which then undergoes a site-specific hydrolysis of pro-IL-1 to generate mature IL-1, thereby activating the related signaling pathways to mediate the inflammatory cascades (40, 54)
Mar/Apr 2020;41(2):289-299
Finally, ultrastructural analysis using electron microscopy revealed that GHRP-6 preserved cardiomyocyte integrity at the organelle level
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