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A randomized, double-blind, cross-over protocol was conducted, entailing the administration of NAC (2g/day) for 60 days and then placebo for another 60 days (or vice versa)

1) Muscle Protein Synthesis and Hypertrophy Support IGF-1 signaling couples training to mTOR activation, increasing muscle protein synthesis ability, an effect consistently reported in human-focused reviews , 1 connecting resistance exercise, nutrient timing, and IGF-1 pathway responsiveness

Lean proteins can help preserve muscle

Moreover, interventions targeting oxidative stress, informed by 8-OHdG levels, could hold promise in mitigating IBD progression