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There is one differential equation for each substrate that says that the rate of change of the concentration of the substrate is the sum of the reaction velocities (M/hr) that produce it minus the sum of the reaction velocities that use it

doi: 10.1111/j.1749-6632.1986.tb51254.x 17 SamokhinaEPopovaIMalkovAIvanovAIPapadiaDOsypovAet al

Additionally, GnRH focused drugs, such as triptorelin and cetrorelix, are recommended to avoid ovarian hyperstimulation syndrome in fertility treatments and improve outcomes