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The endocrinologist I have spoken with regularly about this has mentioned that semaglutide is more muscle sparing than Mounjaro, which raises interesting points about how wide this market may be in terms of each modality perhaps retaining a market share for a very specific type of body composition requirement

Estimated fat mass fell by 9.9 lbs (4.5 kg) in the treatment group versus 1.5 lbs (0.7 kg) in placebo, and estimated visceral fat area dropped by 5.04 in (32.5 cm) versus 1.39 in (9.1 cm) [4]

Hot flashes cause sudden, intense heat with excessive sweating, depleting both water and electrolytes