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67 Non-proliferative astrogliosis typically occurs in neural tissue that is responding to a pathology but is not overtly damaged and retains its basic tissue architecture, for example (i) during diffuse neuroinflammation caused by peripheral exposure to microbial antigens such as lipopolysaccharide (LPS), 68,69 (ii) in tissue regions that are at a distance from focal lesions (diaschisis) caused by stroke, trauma or autoimmune attack, 8,70 or (iii) in tissue undergoing neurodegenerative changes
Goncalves R, Bose R
Injectable therapies inherently carry risks that necessitate professional oversight
Impact of genetic polymorphisms in CYP2C9 and CYP2C19 on the pharmacokinetics of clinically used drugs
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