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an explanation may be that the generation of hydrogen peroxide by the polymorphonuclear neutrophiles might cause a decrease in the quantity of reduced glutathione, whose function is to eliminate, from the red cell, the accumulated metabolites that oxidate the sulfhydryl groups formed by the oxidative stress and therefore decreasing the protective capacity of the cell
Of note, an enormous number of the interactions between the genes involved obscure the final outcome
Cahana, I
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