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drinking 100 mL of water after 12 hours of water avoidance also led to improved performance on the same cognitive test 234 Study 4 Study Design: RCT Subjects: 92 college students Dose: 200 mL (about 7 ounces) of water every two hours (totaling 1.6 liters or almost 7 cups per day) vs 100 mL every two hours or 110 mL every hour Results: 200 mL every two hours had the best effects on mood and cognitive performance 235 Study 5 Study Design: Intervention crossover trial Subjects: 75 children 911 years old Dose: 2.5 liters of water per day for four days versus ordinary (presumably insufficient) water intake or restricted water intake Results: Improved performance on certain cognitive tests with greater water intake than with ordinary intake 236 Study 6 Study Design: Observational/Correlational Subjects: 230 adolescents Results: Higher hydration status was correlated with better cognitive performance

Lamba, a veteran of more than 30 years across pharmaceuticals and biotechnology, previously served as CEO of Zosano Pharma

It has also been approved by the FDA as a weight loss drug, and studies have shown that it does, in fact, help with weight loss by curbing appetite and optimizing the function of the rate at which food is transferred from the stomach to the intestines

Statistical analysis All data were subjected to Analysis of Variance (ANOVA), followed by Tukeys and Kramers multiple comparison tests when significant (p 0.05)