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Patients with this condition cannot absorb B12 from food or oral supplements and require lifelong intramuscular replacement therapy
It combines the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK) with copper(II) to form a small peptidemetal complex that is also found in human fluids and tissue matrices
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MOTS-c safety data comes from animals plus one analog (CB4211) human Phase 1 trial
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