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The clustering between specific biological and clinical features has been postulated to identify a theoretical dimension labelled immuno-metabolic depression (IMD) [2] (aligning with the Research Domain Criteria (RDoC) framework [52]
Contact your GP or bariatric team promptly if you experience: Repeated fainting or loss of consciousness Blood pressure readings consistently below 90/60 mmHg Severe dizziness that prevents normal daily activities Signs of significant dehydration, such as very dark urine, dry mouth, or no urination for more than eight hours Chest pain, shortness of breath, or palpitations alongside low blood pressure Severe abdominal pain, black or tarry stools, fever, or rigors alongside low blood pressure, as these may indicate early post-operative complications requiring urgent assessment Symptoms that are worsening rather than improving over time If you are unsure and it is not an emergency, contact NHS 111 for urgent advice
Upon reconstitution, store aliquots at 28 C or 20 C and use within recommended time frames, minimizing repeated freezethaw cycles
adults have overweight or obesity
