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Its less effective for hair loss caused by autoimmune conditions such as alopecia areata, scarring alopecia, or complete baldness, in which follicles are already gone
This introduces a formidable variable that can mask the true effects of the compound you're studying or create false positives
While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker, L-NAME (prothrombotic) and the NOS-substrate L-arginine (antithrombotic), were little investigated
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