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Pharmacokinetic characterisation is comparatively thin, but distribution and elimination have been profiled in rats and dogs in a 2023 pharmacokinetic study (PMC9794587), which is useful context because most claims about systemic healing rest on animal exposure data rather than validated human pharmacology
Giorgio De Simoni (CNR-NANO, Pisa) for the valuable help in scanning electron microscopy imaging
These are pea-sized or smaller, mildly firm to the touch, and typically painless
It can reveal degradation if the color changes significantly over time
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