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Genetic toxicology testing (Ames test, chromosomal aberration assays, micronucleus testing) returned negative results
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Clinical results: The SURMOUNT-1 trial, published in the New England Journal of Medicine, showed tirzepatide produced average weight loss of 20.9 percent at the 15 mg dose
Mechanistic differences: Matrixyl acts as a matrikine -- a peptide fragment derived from extracellular matrix proteins that signals cells to increase collagen synthesis
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