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These defense mechanisms can be broadly categorized into the canonical glutathione peroxidase 4 (GPX4)-dependent pathway and non-canonical, independent pathways

Therefore, the subsequent breakdown of such proteins results in the release of methylated arginine derivatives: NG-monomethyl-L-arginine (L-NMMA), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) [139]

The human body has a complex mechanism for maintaining the levels of blood pressure, including the renin-angiotensin-aldosterone system, natriuretic peptides, endothelial-sympathetic nervous system, and the immune system (134)

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