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Moisture control stands as the second most critical consideration, as peptide compounds undergo hydrolysis when exposed to humidity

Real-world persistence is low: about half discontinue within a year and roughly three-quarters within two years , often due to cost or side effectsraising the risk of rebound weight and lost health gains (Scientific American on discontinuation rates)

Muscle loss slows metabolism: without enough protein and resistance training, you may lose lean mass, making regain more likely (see prevention plan below)

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