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Blood sugar concerns may apply: Growth hormone pathways can affect glucose, insulin sensitivity, and A1c in some individuals

Ipamorelin: Targets ghrelin receptors

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Furthermore, the application of a multifunctional agonist targeting the GLP-1, GIP, and delta-opioid (DOR) receptorssuch as DPDPErepresents a novel therapeutic strategy for obesity, particularly given that DOR activation has been shown to independently improve glucose homeostasis (Olianas et al., 2011) and insulin sensitivity (Meulebrouck et al., 2024), as well as regulating emotional aspects of eating behavior (Wassum et al., 2009