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Semaglutide and tirzepatide produce weight loss of a magnitude that nutrient injections have never approached, with a real trial base behind them
This multi-system approach makes IV infusions particularly valuable when hydration and nutrient replenishment are both priorities
Importantly, clinical outcomes have been mixed: the large LOVIT randomized trial in adults with sepsis (Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit, Lamontagne and colleagues, New England Journal of Medicine, 2022, n=863) found that high-dose IV vitamin C was associated with a higher risk of death or persistent organ dysfunction than placebo
For combination research at the standard 1:1 ratio, the practical advantages add up
