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Being water-soluble, the effects of vitamin B12 can take place immediately when administered through injections

For instance, deficiencies in both could cause fatigue, but nerve pain was unique to B12, and bone pain was associated with a D deficiency

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According to the National Institutes of Health (NIH) , zinc plays a role in: Immune cell development and signaling Antioxidant activity Wound healing and tissue integrity Cellular growth and repair Even marginal zinc deficiency may impair immune response and prolong recovery from illness