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The bioluminescence resonance energy transfer 2 (BRET2) ratio was calculated (515/400) and the time point corresponding to maximal dissociation was used to generate doseresponse curves

As a result, patients must be 18 years or older and: Have type 2 diabetes and a BMI of 30 or more Have type 2 diabetes and a BMI of 27 with one or more weight-related health conditions

Simple, honest statements work well: you had a late lunch and want something light, your stomach has been sensitive so you're keeping it simple, or you're pacing yourself throughout the day