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granulosus TGR for each compound is shown (compound structures can be found in Table S1)
Jumping straight to 100+ mg daily can increase side effects like nausea or fatigue
This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)
The instrument operated in data-dependent acquisition mode in positive polarity
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