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A potent CysLT1 receptor antagonist, montelukast inhibits the activation of the NF-B pathway and secretion of IL-6 and IL-8 in FLS (165), next to reducing the disease incidence and its activity (166)

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These products have not received the safety and quality review of the FDA, and have not adequately been tested on humans like other more rigorously tested products like GLP-1 drugs