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People who are pregnant or breastfeeding should avoid GLP-1 medication , and certain health conditions may make this type of weight loss treatment unsafe
It was the first large, rigorous head-to-head study between these two medications and was published in the New England Journal of Medicine in May 2025
A case series suggests that treatment with the incretin-based agents semaglutide and tirzepatide may trigger dysesthesia or allodynia in some individuals
The combination produces greater cardiovascular improvement than either intervention alone
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