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Whether people maintain their weight loss on the pill over two, three, or five years remains to be seen
Activation of the 2 -adrenergic pathway is the main mechanism by which insulin secretion is inhibited by the SNS 21 hence our strategy was to activate 2 adrenergic receptors on pancreatic -cells to test if this would counteract the hypothesised decrease in SNS activity triggered by OB GLP-1R activation in WD mice
2014;9(7): e100152
References Lim HW, Grimes PE, Agbai O, Hamzavi I, Henderson M, Haddican M, Linkner RV, Lebwohl M
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