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Firstly the Review was based on research papers that were very suspect and involved groups of individuals that did not represent a wide cross section of society (the primary study was of mainly elderly males)
Structural peptides used in wound healing research (BPC-157, TB-500) operate through angiogenesis and tissue remodeling pathways with minimal central nervous system (CNS) penetration
TB 500, as a synthetic peptide corresponding to thymosin beta 4, was evaluated for its potential role in microRNA-mediated regulatory mechanisms
[PMID: 36206677] PubMed record related to this compound for laboratory literature review
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